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Sesquiterpene Lactone Deoxyelephantopin Isolated from Elephantopus scaber and Its Derivative DETD-35 Suppress BRAF(V600E) Mutant Melanoma Lung Metastasis in Mice

Melanoma is a highly metastatic disease with an increasing rate of incidence worldwide. It is treatment refractory and has poor clinical prognosis; therefore, the development of new therapeutic agents for metastatic melanoma are urgently required. In this study, we created a lung-seeking A375LM5(IF4...

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Detalles Bibliográficos
Autores principales: Cvetanova, Biljana, Li, Meng-Yi, Yang, Chung-Chih, Hsiao, Pei-Wen, Yang, Yu-Chih, Feng, Jia-Hua, Shen, Ya-Ching, Nakagawa-Goto, Kyoko, Lee, Kuo-Hsiung, Shyur, Lie-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004649/
https://www.ncbi.nlm.nih.gov/pubmed/33810045
http://dx.doi.org/10.3390/ijms22063226