Synthesis of New Water Soluble β-Cyclodextrin@Curcumin Conjugates and In Vitro Safety Evaluation in Primary Cultures of Rat Cortical Neurons

Self-aggregation of Curcumin (Cur) in aqueous biological environment decreases its bioavailability and in vivo therapeutic efficacy, which hampers its clinical use as candidate for reducing risk of neurodegenerative diseases. Here, we focused on the design of new Cur- β-Cyclodextrin nanoconjugates t...

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Detalles Bibliográficos
Autores principales: Ben Mihoub, Amina, Acherar, Samir, Frochot, Céline, Malaplate, Catherine, Yen, Frances T., Arab-Tehrany, Elmira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004725/
https://www.ncbi.nlm.nih.gov/pubmed/33806807
http://dx.doi.org/10.3390/ijms22063255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004725/
https://www.ncbi.nlm.nih.gov/pubmed/33806807
http://dx.doi.org/10.3390/ijms22063255

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