Ablation of Acid Ceramidase Impairs Autophagy and Mitochondria Activity in Melanoma Cells

Cutaneous melanoma is often resistant to therapy due to its high plasticity, as well as its ability to metabolise chemotherapeutic drugs. Sphingolipid signalling plays a pivotal role in its progression and metastasis. One of the ways melanoma alters sphingolipid rheostat is via over-expression of ly...

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Detalles Bibliográficos
Autores principales: Lai, Michele, La Rocca, Veronica, Amato, Rachele, Freer, Giulia, Costa, Mario, Spezia, Pietro Giorgio, Quaranta, Paola, Lombardo, Giuseppe, Piomelli, Daniele, Pistello, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004726/
https://www.ncbi.nlm.nih.gov/pubmed/33806766
http://dx.doi.org/10.3390/ijms22063247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004726/
https://www.ncbi.nlm.nih.gov/pubmed/33806766
http://dx.doi.org/10.3390/ijms22063247

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