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Ablation of Acid Ceramidase Impairs Autophagy and Mitochondria Activity in Melanoma Cells
Cutaneous melanoma is often resistant to therapy due to its high plasticity, as well as its ability to metabolise chemotherapeutic drugs. Sphingolipid signalling plays a pivotal role in its progression and metastasis. One of the ways melanoma alters sphingolipid rheostat is via over-expression of ly...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004726/ https://www.ncbi.nlm.nih.gov/pubmed/33806766 http://dx.doi.org/10.3390/ijms22063247 |