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Transglycosylation Activity of Engineered Bifidobacterium Lacto-N-Biosidase Mutants at Donor Subsites for Lacto-N-Tetraose Synthesis

The health benefits of human milk oligosaccharides (HMOs) make them attractive targets as supplements for infant formula milks. However, HMO synthesis is still challenging and only two HMOs have been marketed. Engineering glycoside hydrolases into transglycosylases may provide biocatalytic routes to...

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Detalles Bibliográficos
Autores principales: Castejón-Vilatersana, Mireia, Faijes, Magda, Planas, Antoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004761/
https://www.ncbi.nlm.nih.gov/pubmed/33810098
http://dx.doi.org/10.3390/ijms22063230