Advances in the Formulation and Assembly of Non-Cationic Lipid Nanoparticles for the Medical Application of Gene Therapeutics

Lipid nanoparticles have become increasingly popular delivery platforms in the field of gene therapy, but bench-to-bedside success has been limited. Many liposomal gene vectors are comprised of synthetic cationic lipids, which are associated with lipid-induced cytotoxicity and immunogenicity. Natura...

Descripción completa

Detalles Bibliográficos
Autores principales: Fisher, Richard K., West, Phillip C., Mattern-Schain, Samuel I., Best, Michael D., Kirkpatrick, Stacy S., Dieter, Raymond A., Arnold, Joshua D., Buckley, Michael R., McNally, Michael M., Freeman, Michael B., Grandas, Oscar H., Mountain, Deidra J. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004789/
https://www.ncbi.nlm.nih.gov/pubmed/33807086
http://dx.doi.org/10.3390/nano11030825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004789/
https://www.ncbi.nlm.nih.gov/pubmed/33807086
http://dx.doi.org/10.3390/nano11030825

Ejemplares similares