The Epithelial–Mesenchymal Transcription Factor SNAI1 Represses Transcription of the Tumor Suppressor miRNA let-7 in Cancer

SIMPLE SUMMARY: When cells undergo epithelial–mesenchymal transition (EMT) they gain characteristics of stem cells. We investigated the mechanism by which the EMT transcription factor SNAI1 induces stem cell features. In these studies, we observed that SNAI1 represses a microRNA that maintains diffe...

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Detalles Bibliográficos
Autores principales: Wang, Hanmin, Chirshev, Evgeny, Hojo, Nozomi, Suzuki, Tise, Bertucci, Antonella, Pierce, Michael, Perry, Christopher, Wang, Ruining, Zink, Jeffrey, Glackin, Carlotta A., Ioffe, Yevgeniya J., Unternaehrer, Juli J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004805/
https://www.ncbi.nlm.nih.gov/pubmed/33806868
http://dx.doi.org/10.3390/cancers13061469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004805/
https://www.ncbi.nlm.nih.gov/pubmed/33806868
http://dx.doi.org/10.3390/cancers13061469

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