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The Epithelial–Mesenchymal Transcription Factor SNAI1 Represses Transcription of the Tumor Suppressor miRNA let-7 in Cancer
SIMPLE SUMMARY: When cells undergo epithelial–mesenchymal transition (EMT) they gain characteristics of stem cells. We investigated the mechanism by which the EMT transcription factor SNAI1 induces stem cell features. In these studies, we observed that SNAI1 represses a microRNA that maintains diffe...
Autores principales: | Wang, Hanmin, Chirshev, Evgeny, Hojo, Nozomi, Suzuki, Tise, Bertucci, Antonella, Pierce, Michael, Perry, Christopher, Wang, Ruining, Zink, Jeffrey, Glackin, Carlotta A., Ioffe, Yevgeniya J., Unternaehrer, Juli J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004805/ https://www.ncbi.nlm.nih.gov/pubmed/33806868 http://dx.doi.org/10.3390/cancers13061469 |
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