Potent Neutralization Antibodies Induced by a Recombinant Trimeric Spike Protein Vaccine Candidate Containing PIKA Adjuvant for COVID-19

The structures of immunogens that elicit the most potent neutralization antibodies to prevent COVID-19 infection are still under investigation. In this study, we tested the efficacy of a recombinant trimeric Spike protein containing polyI:C (PIKA) adjuvant in mice immunized by a 0–7–14 day schedule....

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Detalles Bibliográficos
Autores principales: Tong, Jiao, Zhu, Chenxi, Lai, Hanyu, Feng, Chunchao, Zhou, Dapeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004863/
https://www.ncbi.nlm.nih.gov/pubmed/33810026
http://dx.doi.org/10.3390/vaccines9030296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004863/
https://www.ncbi.nlm.nih.gov/pubmed/33810026
http://dx.doi.org/10.3390/vaccines9030296

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