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Role of the ROS-JNK Signaling Pathway in Hypoxia-Induced Atrial Fibrotic Responses in HL-1 Cardiomyocytes

By promoting atrial structural remodeling, atrial hypoxia contributes to the development of the atrial fibrillation substrate. Our study aimed to investigate the modulatory effect of hypoxia on profibrotic activity in cultured HL-1 cardiomyocytes and explore the possible signaling transduction mecha...

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Detalles Bibliográficos
Autores principales: Tsai, Chin-Feng, Yang, Shun-Fa, Lo, Chien-Hsien, Chu, Hsiao-Ju, Ueng, Kwo-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004875/
https://www.ncbi.nlm.nih.gov/pubmed/33806765
http://dx.doi.org/10.3390/ijms22063249