Hereditary Spastic Paraplegia: From Genes, Cells and Networks to Novel Pathways for Drug Discovery

Hereditary spastic paraplegia (HSP) is a diverse group of Mendelian genetic disorders affecting the upper motor neurons, specifically degeneration of their distal axons in the corticospinal tract. Currently, there are 80 genes or genomic loci (genomic regions for which the causative gene has not bee...

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Detalles Bibliográficos
Autor principal: Mackay-Sim, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004882/
https://www.ncbi.nlm.nih.gov/pubmed/33810178
http://dx.doi.org/10.3390/brainsci11030403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004882/
https://www.ncbi.nlm.nih.gov/pubmed/33810178
http://dx.doi.org/10.3390/brainsci11030403

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