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Persistent Inflammatory Stimulation Drives the Conversion of MSCs to Inflammatory CAFs That Promote Pro-Metastatic Characteristics in Breast Cancer Cells

SIMPLE SUMMARY: Breast cancer progression is prominently regulated by the persistent presence of inflammatory mediators and by stromal cells that are located in the tumors. Here, we connected these two elements by demonstrating that potent pro-inflammatory cytokines (tumor necrosis factor α and inte...

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Detalles Bibliográficos
Autores principales: Rubinstein-Achiasaf, Linor, Morein, Dina, Ben-Yaakov, Hagar, Liubomirski, Yulia, Meshel, Tsipi, Elbaz, Eti, Dorot, Orly, Pichinuk, Edward, Gershovits, Michael, Weil, Miguel, Ben-Baruch, Adit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004890/
https://www.ncbi.nlm.nih.gov/pubmed/33806906
http://dx.doi.org/10.3390/cancers13061472