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SCRaMbLE: A Study of Its Robustness and Challenges through Enhancement of Hygromycin B Resistance in a Semi-Synthetic Yeast

Recent advances in synthetic genomics launched the ambitious goal of generating the first synthetic designer eukaryote, based on the model organism Saccharomyces cerevisiae (Sc2.0). Excitingly, the Sc2.0 project is now nearing its completion and SCRaMbLE, an accelerated evolution tool implemented by...

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Detalles Bibliográficos
Autores principales: Ong, Jun Yang, Swidah, Reem, Monti, Marco, Schindler, Daniel, Dai, Junbiao, Cai, Yizhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004914/
https://www.ncbi.nlm.nih.gov/pubmed/33806931
http://dx.doi.org/10.3390/bioengineering8030042