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Modulation of Ion Transport to Restore Airway Hydration in Cystic Fibrosis
Cystic fibrosis (CF) is a life-limiting genetic disorder caused by loss-of-function mutations in the gene which codes for the CF transmembrane conductance regulator (CFTR) Cl(−) channel. Loss of Cl(−) secretion across the apical membrane of airway lining epithelial cells results in dehydration of th...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004921/ https://www.ncbi.nlm.nih.gov/pubmed/33810137 http://dx.doi.org/10.3390/genes12030453 |