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Modulation of Ion Transport to Restore Airway Hydration in Cystic Fibrosis

Cystic fibrosis (CF) is a life-limiting genetic disorder caused by loss-of-function mutations in the gene which codes for the CF transmembrane conductance regulator (CFTR) Cl(−) channel. Loss of Cl(−) secretion across the apical membrane of airway lining epithelial cells results in dehydration of th...

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Detalles Bibliográficos
Autores principales:	Reihill, James A., Douglas, Lisa E. J., Martin, S. Lorraine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004921/ https://www.ncbi.nlm.nih.gov/pubmed/33810137 http://dx.doi.org/10.3390/genes12030453

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