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The GNAQ T96S Mutation Affects Cell Signaling and Enhances the Oncogenic Properties of Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC), the most common malignant tumor in the liver, grows and metastasizes rapidly. Despite advances in treatment modalities, the five-year survival rate of HCC remains less than 30%. We sought genetic mutations that may affect the oncogenic properties of HCC, using The Can...

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Detalles Bibliográficos
Autores principales: Choi, Eugene, Park, Sung Jean, Lee, Gunhee, Yoon, Seung Kew, Lee, Minho, Lee, Suk Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004934/
https://www.ncbi.nlm.nih.gov/pubmed/33807071
http://dx.doi.org/10.3390/ijms22063284