Vaccine Efficacy of Self-Assembled Multimeric Protein Scaffold Particles Displaying the Glycoprotein Gn Head Domain of Rift Valley Fever Virus

Compared to free antigens, antigens immobilized on scaffolds, such as nanoparticles, generally show improved immunogenicity. Conventionally, antigens are conjugated to scaffolds through genetic fusion or chemical conjugation, which may result in impaired assembly or heterogeneous binding and orienta...

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Detalles Bibliográficos
Autores principales: Wichgers Schreur, Paul J., Tacken, Mirriam, Gutjahr, Benjamin, Keller, Markus, van Keulen, Lucien, Kant, Jet, van de Water, Sandra, Lin, Yanyin, Eiden, Martin, Rissmann, Melanie, von Arnim, Felicitas, König, Rebecca, Brix, Alexander, Charreyre, Catherine, Audonnet, Jean-Christophe, Groschup, Martin H., Kortekaas, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005036/
https://www.ncbi.nlm.nih.gov/pubmed/33806789
http://dx.doi.org/10.3390/vaccines9030301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005036/
https://www.ncbi.nlm.nih.gov/pubmed/33806789
http://dx.doi.org/10.3390/vaccines9030301

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