A Non-Toxic Concentration of Telomerase Inhibitor BIBR1532 Fails to Reduce TERT Expression in a Feeder-Free Induced Pluripotent Stem Cell Model of Human Motor Neurogenesis

Several studies have shown that human induced pluripotent stem cell (iPSC)-derivatives are essentially fetal in terms of their maturational status. Inducing ageing in iPSC-motor neuron (MN) models of amyotrophic lateral sclerosis (ALS) has the potential to capture pathology with higher fidelity and...

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Detalles Bibliográficos
Autores principales: Pandya, Virenkumar A., Crerar, Hamish, Mitchell, Jamie S., Patani, Rickie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005146/
https://www.ncbi.nlm.nih.gov/pubmed/33806803
http://dx.doi.org/10.3390/ijms22063256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005146/
https://www.ncbi.nlm.nih.gov/pubmed/33806803
http://dx.doi.org/10.3390/ijms22063256

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