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Key Matrix Remodeling Enzymes: Functions and Targeting in Cancer

SIMPLE SUMMARY: Proteolytic enzymes, such as matrix metalloproteinases, plasminogen activators and cathepsins, as well as non-proteolytic enzymatic partners, such as heparanase and hyaluron-idases, play key roles in the propagation and metastatic potential of cancer cells. This article aims to revis...

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Detalles Bibliográficos
Autores principales: Piperigkou, Zoi, Kyriakopoulou, Konstantina, Koutsakis, Christos, Mastronikolis, Stylianos, Karamanos, Nikos K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005147/
https://www.ncbi.nlm.nih.gov/pubmed/33809973
http://dx.doi.org/10.3390/cancers13061441