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‘Statistical Irreproducibility’ Does Not Improve with Larger Sample Size: How to Quantify and Address Disease Data Multimodality in Human and Animal Research

Poor study reproducibility is a concern in translational research. As a solution, it is recommended to increase sample size (N), i.e., add more subjects to experiments. The goal of this study was to examine/visualize data multimodality (data with >1 data peak/mode) as cause of study irreproducibi...

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Detalles Bibliográficos
Autores principales: Basson, Abigail R., Cominelli, Fabio, Rodriguez-Palacios, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005169/
https://www.ncbi.nlm.nih.gov/pubmed/33806843
http://dx.doi.org/10.3390/jpm11030234