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Plasma glial fibrillary acidic protein detects Alzheimer pathology and predicts future conversion to Alzheimer dementia in patients with mild cognitive impairment

INTRODUCTION: Plasma glial fibrillary acidic protein (GFAP) is a marker of astroglial activation and astrocytosis. We assessed the ability of plasma GFAP to detect Alzheimer’s disease (AD) pathology in the form of AD-related amyloid-β (Aβ) pathology and conversion to AD dementia in a mild cognitive...

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Detalles Bibliográficos
Autores principales: Cicognola, Claudia, Janelidze, Shorena, Hertze, Joakim, Zetterberg, Henrik, Blennow, Kaj, Mattsson-Carlgren, Niklas, Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005231/
https://www.ncbi.nlm.nih.gov/pubmed/33773595
http://dx.doi.org/10.1186/s13195-021-00804-9