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Stem Cell Factor Neutralization Protects From Severe Anaphylaxis in a Murine Model of Food Allergy

Food allergy is a growing public health problem with ~15 million people affected in the United States. In allergic food disease, IgE on mast cells bind to ingested antigens leading to the activation and degranulation of mast cells. Stem cell factor (SCF) is mast cell growth and activation factor tha...

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Detalles Bibliográficos
Autores principales: Ptaschinski, Catherine, Rasky, Andrew J., Fonseca, Wendy, Lukacs, Nicholas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005333/
https://www.ncbi.nlm.nih.gov/pubmed/33786039
http://dx.doi.org/10.3389/fimmu.2021.604192