Phospho-ablation of cardiac sodium channel Na(v)1.5 mitigates susceptibility to atrial fibrillation and improves glucose homeostasis under conditions of diet-induced obesity

BACKGROUND: Atrial fibrillation (AF) is the most common sustained arrhythmia, with growing evidence identifying obesity as an important risk factor for the development of AF. Although defective atrial myocyte excitability due to stress-induced remodeling of ion channels is commonly observed in the s...

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Detalles Bibliográficos
Autores principales: Dewal, Revati S., Greer-Short, Amara, Lane, Cemantha, Nirengi, Shinsuke, Manzano, Pedro Acosta, Hernández-Saavedra, Diego, Wright, Katherine R., Nassal, Drew, Baer, Lisa A., Mohler, Peter J., Hund, Thomas J., Stanford, Kristin I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005377/
https://www.ncbi.nlm.nih.gov/pubmed/33500550
http://dx.doi.org/10.1038/s41366-021-00742-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005377/
https://www.ncbi.nlm.nih.gov/pubmed/33500550
http://dx.doi.org/10.1038/s41366-021-00742-4

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