Activation of PI3K/AKT/mTOR Pathway Causes Drug Resistance in Breast Cancer

Although chemotherapy, targeted therapy and endocrine therapy decrease rate of disease recurrence in most breast cancer patients, many patients exhibit acquired resistance. Hyperactivation of the PI3K/AKT/mTOR pathway is associated with drug resistance and cancer progression. Currently, a number of...

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Detalles Bibliográficos
Autores principales: Dong, Chao, Wu, Jiao, Chen, Yin, Nie, Jianyun, Chen, Ceshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005514/
https://www.ncbi.nlm.nih.gov/pubmed/33790792
http://dx.doi.org/10.3389/fphar.2021.628690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005514/
https://www.ncbi.nlm.nih.gov/pubmed/33790792
http://dx.doi.org/10.3389/fphar.2021.628690

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