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Donepezil Ameliorates Pulmonary Arterial Hypertension by Inhibiting M2-Macrophage Activation

Background: The beneficial effects of parasympathetic stimulation in pulmonary arterial hypertension (PAH) have been reported. However, the specific mechanism has not been completely clarified. Donepezil, an oral cholinesterase inhibitor, enhances parasympathetic activity by inhibiting acetylcholine...

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Detalles Bibliográficos
Autores principales: Qiu, Haihua, Zhang, Yibo, Li, Zhongyu, Jiang, Ping, Guo, Shuhong, He, Yi, Guo, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005547/
https://www.ncbi.nlm.nih.gov/pubmed/33791350
http://dx.doi.org/10.3389/fcvm.2021.639541