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Adenylate Kinase 4 Promotes Inflammatory Gene Expression via Hif1α and AMPK in Macrophages

Macrophages comprise the front line of defense against various pathogens. Classically activated macrophages (M1), induced by IFN-γ and LPS, highly express inflammatory cytokines and contribute to inflammatory processes. By contrast, alternatively activated macrophages (M2) are induced by IL-4 and IL...

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Detalles Bibliográficos
Autores principales: Chin, Wei-Yao, He, Chi-Ying, Chow, Tsun Wai, Yu, Qi-You, Lai, Liang-Chuan, Miaw, Shi-Chuen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005550/
https://www.ncbi.nlm.nih.gov/pubmed/33790902
http://dx.doi.org/10.3389/fimmu.2021.630318