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The P2X(7) Receptor in Microglial Cells Modulates the Endolysosomal Axis, Autophagy, and Phagocytosis

Microglial cells regulate neural homeostasis by coordinating both immune responses and clearance of debris, and the P2X(7) receptor for extracellular ATP plays a central role in both functions. The P2X(7) receptor is primarily known in microglial cells for its immune signaling and NLRP3 inflammasome...

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Detalles Bibliográficos
Autores principales: Campagno, Keith E., Mitchell, Claire H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005553/
https://www.ncbi.nlm.nih.gov/pubmed/33790743
http://dx.doi.org/10.3389/fncel.2021.645244