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The P2X(7) Receptor in Microglial Cells Modulates the Endolysosomal Axis, Autophagy, and Phagocytosis
Microglial cells regulate neural homeostasis by coordinating both immune responses and clearance of debris, and the P2X(7) receptor for extracellular ATP plays a central role in both functions. The P2X(7) receptor is primarily known in microglial cells for its immune signaling and NLRP3 inflammasome...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005553/ https://www.ncbi.nlm.nih.gov/pubmed/33790743 http://dx.doi.org/10.3389/fncel.2021.645244 |