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How the Discovery of the CD4/CD8-p56(lck) Complexes Changed Immunology and Immunotherapy
The past 25 years have seen enormous progress in uncovering the receptors and signaling mechanisms on T-cells that activate their various effecter functions. Until the late 1980s, most studies on T-cells had focused on the influx of calcium and the levels of cAMP/GMP in T-cells. My laboratory then u...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005572/ https://www.ncbi.nlm.nih.gov/pubmed/33791292 http://dx.doi.org/10.3389/fcell.2021.626095 |