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Tetramethylpyrazine Improves Cognitive Impairment and Modifies the Hippocampal Proteome in Two Mouse Models of Alzheimer's Disease

Alzheimer's disease (AD), one of the most common neurodegenerative diseases, has no effective treatment. We studied the potential effects of tetramethylpyrazine (TMP), an alkaloid in the rhizome of Ligusticum chuanxiong Hort. used in Traditional Chinese Medicine (chuānxiong) to treat ischemic s...

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Detalles Bibliográficos
Autores principales: Huang, Xianfeng, Yang, Jinyao, Huang, Xi, Zhang, Zaijun, Liu, Jianjun, Zou, Liangyu, Yang, Xifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005584/
https://www.ncbi.nlm.nih.gov/pubmed/33791294
http://dx.doi.org/10.3389/fcell.2021.632843