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Population Pharmacokinetic Study of Cefathiamidine in Infants With Augmented Renal Clearance

Objectives: Augmented renal clearance (ARC) of primarily renally eliminated antibacterial agents may result in subtherapeutic antibiotic concentrations and, as a consequence, worse clinical outcomes. Cefathiamidine is frequently used as empirical antimicrobial therapy in children with ARC, but pharm...

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Detalles Bibliográficos
Autores principales: Du, Bin, Zhou, Yue, Tang, Bo-Hao, Wu, Yue-E, Yang, Xin-Mei, Shi, Hai-Yan, Yao, Bu-Fan, Hao, Guo-Xiang, You, Dian-Ping, van den Anker, John, Zheng, Yi, Zhao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005605/
https://www.ncbi.nlm.nih.gov/pubmed/33790793
http://dx.doi.org/10.3389/fphar.2021.630047