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MiR-29a Knockout Aggravates Neurological Damage by Pre-polarizing M1 Microglia in Experimental Rat Models of Acute Stroke

OBJECTIVE: By exploring the effects of miR-29a-5p knockout on neurological damage after acute ischemic stroke, we aim to deepen understanding of the molecular mechanisms of post-ischemic injury and thus provide new ideas for the treatment of ischemic brain injury. METHODS: miR-29a-5p knockout rats a...

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Detalles Bibliográficos
Autores principales: Zhao, Fangfang, Zhao, Haiping, Fan, Junfen, Wang, Rongliang, Han, Ziping, Tao, Zhen, Zheng, Yangmin, Yan, Feng, Huang, Yuyou, Yu, Lei, Zhang, Xu, Qi, Xiaolong, Zhang, Lianfeng, Luo, Yumin, Ma, Yuanwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005650/
https://www.ncbi.nlm.nih.gov/pubmed/33790947
http://dx.doi.org/10.3389/fgene.2021.642079