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The CREB/KMT5A complex regulates PTP1B to modulate high glucose-induced endothelial inflammatory factor levels in diabetic nephropathy

Diabetic nephropathy (DN) is the primary microvascular complication of diabetes mellitus and may result in end-stage renal disease. The overproduction of various inflammatory factors is involved in the pathogenesis of DN. Protein tyrosine phosphatase 1B (PTP1B) modulates the expression of a series o...

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Detalles Bibliográficos
Autores principales: Huang, Ting, Li, Xue, Wang, Fei, Lu, Lihong, Hou, Wenting, Zhu, Minmin, Miao, Changhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005662/
https://www.ncbi.nlm.nih.gov/pubmed/33782381
http://dx.doi.org/10.1038/s41419-021-03629-4