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Sirt3 in POMC neurons controls energy balance in a sex- and diet-dependent manner

Sirtuin 3 (SIRT3) is one of the seven mammalian sirtuin homologs of the yeast Sir2 gene that has emerged as an important player in the regulation of energy metabolism in peripheral tissues. However, its role in the hypothalamus has not been explored. Herein, we show that the genetic inhibition of SI...

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Detalles Bibliográficos
Autores principales: Quiñones, Mar, Hernández-Bautista, René, Beiroa, Daniel, Heras, Violeta, Torres-Leal, Francisco L., Lam, Brian Y.H., Senra, Ana, Fernø, Johan, Gómez-Valadés, Alicia García, Schwaninger, Markus, Prevot, Vincent, Yeo, Giles, Claret, Marc, López, Miguel, Diéguez, Carlos, Al-Massadi, Omar, Nogueiras, Ruben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005845/
https://www.ncbi.nlm.nih.gov/pubmed/33744652
http://dx.doi.org/10.1016/j.redox.2021.101945