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Sirt3 in POMC neurons controls energy balance in a sex- and diet-dependent manner
Sirtuin 3 (SIRT3) is one of the seven mammalian sirtuin homologs of the yeast Sir2 gene that has emerged as an important player in the regulation of energy metabolism in peripheral tissues. However, its role in the hypothalamus has not been explored. Herein, we show that the genetic inhibition of SI...
Autores principales: | Quiñones, Mar, Hernández-Bautista, René, Beiroa, Daniel, Heras, Violeta, Torres-Leal, Francisco L., Lam, Brian Y.H., Senra, Ana, Fernø, Johan, Gómez-Valadés, Alicia García, Schwaninger, Markus, Prevot, Vincent, Yeo, Giles, Claret, Marc, López, Miguel, Diéguez, Carlos, Al-Massadi, Omar, Nogueiras, Ruben |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005845/ https://www.ncbi.nlm.nih.gov/pubmed/33744652 http://dx.doi.org/10.1016/j.redox.2021.101945 |
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