A Non-Perturbative Molecular Grafting Strategy for Stable and Potent Therapeutic Peptide Ligands

[Image: see text] The gut-derived incretin hormone, glucagon-like peptide-1 (GLP1), plays an important physiological role in attenuating post-prandial blood glucose excursions in part by amplifying pancreatic insulin secretion. Native GLP1 is rapidly degraded by the serine protease, dipeptidyl pepti...

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Detalles Bibliográficos
Autores principales: Sicinski, Kathleen M., Montanari, Vittorio, Raman, Venkata S., Doyle, Jamie R., Harwood, Benjamin N., Song, Yi Chi, Fagan, Micaella P., Rios, Maribel, Haines, David R., Kopin, Alan S., Beinborn, Martin, Kumar, Krishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006168/
https://www.ncbi.nlm.nih.gov/pubmed/33791428
http://dx.doi.org/10.1021/acscentsci.0c01237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006168/
https://www.ncbi.nlm.nih.gov/pubmed/33791428
http://dx.doi.org/10.1021/acscentsci.0c01237

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