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Systematic identification of plausible pathways to potential harm via problem formulation for investigational releases of a population suppression gene drive to control the human malaria vector Anopheles gambiae in West Africa
BACKGROUND: Population suppression gene drive has been proposed as a strategy for malaria vector control. A CRISPR-Cas9-based transgene homing at the doublesex locus (dsxF(CRISPRh)) has recently been shown to increase rapidly in frequency in, and suppress, caged laboratory populations of the malaria...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006393/ https://www.ncbi.nlm.nih.gov/pubmed/33781254 http://dx.doi.org/10.1186/s12936-021-03674-6 |