Systematic identification of plausible pathways to potential harm via problem formulation for investigational releases of a population suppression gene drive to control the human malaria vector Anopheles gambiae in West Africa

BACKGROUND: Population suppression gene drive has been proposed as a strategy for malaria vector control. A CRISPR-Cas9-based transgene homing at the doublesex locus (dsxF(CRISPRh)) has recently been shown to increase rapidly in frequency in, and suppress, caged laboratory populations of the malaria...

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Detalles Bibliográficos
Autores principales: Connolly, John B., Mumford, John D., Fuchs, Silke, Turner, Geoff, Beech, Camilla, North, Ace R., Burt, Austin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006393/
https://www.ncbi.nlm.nih.gov/pubmed/33781254
http://dx.doi.org/10.1186/s12936-021-03674-6

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