MYC Enhances Cholesterol Biosynthesis and Supports Cell Proliferation Through SQLE

Oncogene c-Myc (referred in this report as MYC) promotes tumorigenesis in multiple human cancers. MYC regulates numerous cellular programs involved in cell growth and cell metabolism. Tumor cells exhibit obligatory dependence on cholesterol metabolism, which provides essential membrane components an...

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Detalles Bibliográficos
Autores principales: Yang, Fan, Kou, Junjie, Liu, Zizhao, Li, Wei, Du, Wenjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006431/
https://www.ncbi.nlm.nih.gov/pubmed/33791309
http://dx.doi.org/10.3389/fcell.2021.655889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006431/
https://www.ncbi.nlm.nih.gov/pubmed/33791309
http://dx.doi.org/10.3389/fcell.2021.655889

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