Pyr1-Mediated Pharmacological Inhibition of LIM Kinase Restores Synaptic Plasticity and Normal Behavior in a Mouse Model of Schizophrenia

The search for effective treatments for neuropsychiatric disorders is ongoing, with progress being made as brain structure and neuronal function become clearer. The central roles played by microtubules (MT) and actin in synaptic transmission and plasticity suggest that the cytoskeleton and its modul...

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Detalles Bibliográficos
Autores principales: Gory-Fauré, Sylvie, Powell, Rebecca, Jonckheere, Julie, Lanté, Fabien, Denarier, Eric, Peris, Leticia, Nguyen, Chi Hung, Buisson, Alain, Lafanechère, Laurence, Andrieux, Annie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006432/
https://www.ncbi.nlm.nih.gov/pubmed/33790791
http://dx.doi.org/10.3389/fphar.2021.627995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006432/
https://www.ncbi.nlm.nih.gov/pubmed/33790791
http://dx.doi.org/10.3389/fphar.2021.627995

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