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Human Mast Cell Line HMC1 Expresses Functional Mas-Related G-Protein Coupled Receptor 2

The Mas-related G-protein-coupled receptor X2 (MRGPRX2) is prominently expressed by mast cells and induces degranulation upon binding by different ligands. Its activation has been linked to various mast cell-related diseases, such as chronic spontaneous urticaria, atopic dermatitis and asthma. There...

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Detalles Bibliográficos
Autores principales: Hermans, Maud A. W., van Stigt, Astrid C., van de Meerendonk, Sanne, Schrijver, Benjamin, van Daele, Paul L. A., van Hagen, Petrus M., van Splunter, Marloes, Dik, Willem A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006456/
https://www.ncbi.nlm.nih.gov/pubmed/33790895
http://dx.doi.org/10.3389/fimmu.2021.625284