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Human Mast Cell Line HMC1 Expresses Functional Mas-Related G-Protein Coupled Receptor 2
The Mas-related G-protein-coupled receptor X2 (MRGPRX2) is prominently expressed by mast cells and induces degranulation upon binding by different ligands. Its activation has been linked to various mast cell-related diseases, such as chronic spontaneous urticaria, atopic dermatitis and asthma. There...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006456/ https://www.ncbi.nlm.nih.gov/pubmed/33790895 http://dx.doi.org/10.3389/fimmu.2021.625284 |