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PPARγ is essential for the development of bone marrow erythroblastic island macrophages and splenic red pulp macrophages

Tissue-resident macrophages play a crucial role in maintaining homeostasis. Macrophage progenitors migrate to tissues perinatally, where environmental cues shape their identity and unique functions. Here, we show that the absence of PPARγ affects neonatal development and VCAM-1 expression of splenic...

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Detalles Bibliográficos
Autores principales: Okreglicka, Katarzyna, Iten, Irina, Pohlmeier, Lea, Onder, Lucas, Feng, Qian, Kurrer, Michael, Ludewig, Burkhard, Nielsen, Peter, Schneider, Christoph, Kopf, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006858/
https://www.ncbi.nlm.nih.gov/pubmed/33765133
http://dx.doi.org/10.1084/jem.20191314