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PPARγ is essential for the development of bone marrow erythroblastic island macrophages and splenic red pulp macrophages
Tissue-resident macrophages play a crucial role in maintaining homeostasis. Macrophage progenitors migrate to tissues perinatally, where environmental cues shape their identity and unique functions. Here, we show that the absence of PPARγ affects neonatal development and VCAM-1 expression of splenic...
Autores principales: | Okreglicka, Katarzyna, Iten, Irina, Pohlmeier, Lea, Onder, Lucas, Feng, Qian, Kurrer, Michael, Ludewig, Burkhard, Nielsen, Peter, Schneider, Christoph, Kopf, Manfred |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006858/ https://www.ncbi.nlm.nih.gov/pubmed/33765133 http://dx.doi.org/10.1084/jem.20191314 |
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