Cancer-associated exportin-6 upregulation inhibits the transcriptionally repressive and anticancer effects of nuclear profilin-1

Aberrant expression of nuclear transporters and deregulated subcellular localization of their cargo proteins are emerging as drivers and therapeutic targets of cancer. Here, we present evidence that the nuclear exporter exportin-6 and its cargo profilin-1 constitute a functionally important and freq...

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Detalles Bibliográficos
Autores principales: Zhu, Cuige, Kim, Sun-Joong, Mooradian, Arshag, Wang, Faliang, Li, Ziqian, Holohan, Sean, Collins, Patrick L., Wang, Keren, Guo, Zhanfang, Hoog, Jeremy, Ma, Cynthia X., Oltz, Eugene M., Held, Jason M., Shao, Jieya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006859/
https://www.ncbi.nlm.nih.gov/pubmed/33596420
http://dx.doi.org/10.1016/j.celrep.2021.108749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006859/
https://www.ncbi.nlm.nih.gov/pubmed/33596420
http://dx.doi.org/10.1016/j.celrep.2021.108749

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