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Melatonin Attenuates Sepsis-Induced Small-Intestine Injury by Upregulating SIRT3-Mediated Oxidative-Stress Inhibition, Mitochondrial Protection, and Autophagy Induction

Melatonin reportedly alleviates sepsis-induced multi-organ injury by inducing autophagy and activating class III deacetylase Sirtuin family members (SIRT1–7). However, whether melatonin attenuates small-intestine injury along with the precise underlying mechanism remain to be elucidated. To investig...

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Detalles Bibliográficos
Autores principales: Xu, Siqi, Li, Lulan, Wu, Jie, An, Sheng, Fang, Haihong, Han, Yunyang, Huang, Qiaobing, Chen, Zhongqing, Zeng, Zhenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006917/
https://www.ncbi.nlm.nih.gov/pubmed/33790896
http://dx.doi.org/10.3389/fimmu.2021.625627