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Study of Combinatorial Drug Synergy of Novel Acridone Derivatives With Temozolomide Using in-silico and in-vitro Methods in the Treatment of Drug-Resistant Glioma

Drug resistance is one of the critical challenges faced in the treatment of Glioma. There are only limited drugs available in the treatment of Glioma and among them Temozolomide (TMZ) has shown some effectiveness in treating Glioma patients, however, the rate of recovery remains poor due to the inab...

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Detalles Bibliográficos
Autores principales: Chakravarty, Malobika, Ganguli, Piyali, Murahari, Manikanta, Sarkar, Ram Rup, Peters, Godefridus Johannes, Mayur, Y. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006935/
https://www.ncbi.nlm.nih.gov/pubmed/33791212
http://dx.doi.org/10.3389/fonc.2021.625899