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Mesenchymal Stem Cell-Derived Exosomes Carry MicroRNA-125a to Protect Against Diabetic Nephropathy by Targeting Histone Deacetylase 1 and Downregulating Endothelin-1

BACKGROUND: Mesenchymal stem cell (MSC)-derived exosomes have seen great advances in human disease control in a minimally invasive manner. This research aimed to explore the function of MSC-derived exosomes in diabetic nephropathy (DN) progression and the molecules involved. METHODS: A rat model wit...

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Detalles Bibliográficos
Autores principales: Hao, Yan, Miao, Jie, Liu, Wenjia, Cai, Kangqin, Huang, Xianli, Peng, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006976/
https://www.ncbi.nlm.nih.gov/pubmed/33790607
http://dx.doi.org/10.2147/DMSO.S286191