A heterochromatin inducing protein differentially recognizes self versus foreign genomes

Krüppel-associated box-domain zinc finger protein (KRAB-ZFP) transcriptional repressors recruit TRIM28/KAP1 to heterochromatinize the mammalian genome while also guarding the host by silencing invading foreign genomes. However, how a KRAB-ZFP recognizes target sequences in the natural context of its...

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Detalles Bibliográficos
Autores principales: Burton, Eric M., Akinyemi, Ibukun A., Frey, Tiffany R., Xu, Huanzhou, Li, Xiaofan, Su, Lai Jing, Zhi, Jizu, McIntosh, Michael T., Bhaduri-McIntosh, Sumita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007004/
https://www.ncbi.nlm.nih.gov/pubmed/33730092
http://dx.doi.org/10.1371/journal.ppat.1009447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007004/
https://www.ncbi.nlm.nih.gov/pubmed/33730092
http://dx.doi.org/10.1371/journal.ppat.1009447

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