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Anti-Leptospira immunoglobulin profiling in mice reveals strain specific IgG and persistent IgM responses associated with virulence and renal colonization

Leptospira interrogans is a pathogenic spirochete responsible for leptospirosis, a neglected, zoonotic reemerging disease. Humans are sensitive hosts and may develop severe disease. Some animal species, such as rats and mice can become asymptomatic renal carriers. More than 350 leptospiral serovars...

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Detalles Bibliográficos
Autores principales: Vernel-Pauillac, Frédérique, Murray, Gerald L., Adler, Ben, Boneca, Ivo G., Werts, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007020/
https://www.ncbi.nlm.nih.gov/pubmed/33705392
http://dx.doi.org/10.1371/journal.pntd.0008970