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Anti-Leptospira immunoglobulin profiling in mice reveals strain specific IgG and persistent IgM responses associated with virulence and renal colonization
Leptospira interrogans is a pathogenic spirochete responsible for leptospirosis, a neglected, zoonotic reemerging disease. Humans are sensitive hosts and may develop severe disease. Some animal species, such as rats and mice can become asymptomatic renal carriers. More than 350 leptospiral serovars...
Autores principales: | Vernel-Pauillac, Frédérique, Murray, Gerald L., Adler, Ben, Boneca, Ivo G., Werts, Catherine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007020/ https://www.ncbi.nlm.nih.gov/pubmed/33705392 http://dx.doi.org/10.1371/journal.pntd.0008970 |
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