Identification of a novel conserved signaling motif in CD200 receptor required for its inhibitory function

The inhibitory signaling of CD200 receptor 1 (CD200R) has been attributed to its NPxY signaling motif. However, NPxY-motifs are present in multiple protein families and are mostly known to mediate protein trafficking between subcellular locations rather than signaling. Therefore, we investigated whe...

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Detalles Bibliográficos
Autores principales: Timmerman, Laura M., de Graaf, J. Fréderique, Satravelas, Nikolaos, Kesmir, Çan, Meyaard, Linde, van der Vlist, Michiel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007030/
https://www.ncbi.nlm.nih.gov/pubmed/33780466
http://dx.doi.org/10.1371/journal.pone.0244770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007030/
https://www.ncbi.nlm.nih.gov/pubmed/33780466
http://dx.doi.org/10.1371/journal.pone.0244770

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